December 16, 2009


Posted in Infertility, Life, Work tagged at 1:43 pm by lifebytheday

Just a quick note to say two things:

  1. I hate Metformin.  On Monday night I tried again to up my dose to the prescribed two tabs – and spent the wee hours of Tuesday morning on the toilet, and the subsequent hours on the couch.  I’ve decided to just suck it up and be miserable for a few days, because this yo-yo-ing is NOT pleasant.  I think that the “issues” should go away in a few days, and until then I just have to be careful what I eat. (The only thing I felt like eating for lunch today was turkey and mashed potatoes, so I just ordered – and polished off! – a complete turkey dinner from the diner down the street from work.)  And nope, haven’t done a single couch-to-5k workout since the “rah-rah” first one I blogged about…so all that yummy turkey gravy is just sitting there on my love handles. ;-P
  2. I am sick of work.  I need a new job, or at least a vacation, and CAN NOT WAIT for some time off around Christmas.  Today I sent my boss an email detailing the work I was planning to get done by the end of the week, and explaining how busy and overwhelmed I was…and this is the response I got  – “Okay. We can catch up on all these things this afternoon. There’s a few things on my “to do” list we need to go over.”



November 4, 2009

*WARNING* TMI post – not for the faint of heart-slash-people who know me in real life ;-)

Posted in Infertility tagged , , , at 9:21 am by lifebytheday

So what does gas + constipation + diarrhea + headaches = ???


Apparently, this is what happens when you get all cocky and tell the RE “Nooo…Metformin never bothered ME!”  I know enough other people who have had a terrible time on Metformin to know what the possible side effects were, but I had never noticed them before.  (Side note – I had previously taken 4 extended release tablets (2000 mgs) daily, which my new RE says was way to much for me, and even that didn’t bother me.)  This time around, he wants me to take 2 tabs (1000 mgs) and build it up in my system before we start the next IVF cycle – no problem, right?? 

So Sunday night – after a fabulous day filled with football, friends, and FOOD – I took my 2 tabs, totally forgetting that you’re supposed to work your way up to the prescribed dose (i.e. one tab for a week, and then add the second).  I was up and down all Sunday night, dreaming I was having a (ahem) bowel movement (I know, disgusting and terrifying!) and then running to the bathroom.  I just thought that I had eaten too much…it didn’t register until half way through Monday that I realized I should have only taken one.  So Monday night, I dutifully took my one pill, only to repeat the pattern, and wake up with a headache to boot.  Needless to say, I was not in the mood to schlepp into work yesterday, so I took a sick day and spent it on the couch catching up with my DVR’d shows and Real Sim.ple mags.  It was a nice break –  and I even accomplished some laundry (five loads)!  I still feel crappy today though – hopefully it will wear off soon.

Oh well, just one of many things that I’ll have to suck up over the next few months.  Bring it on! 😉

October 30, 2009

And we’re off…like a herd of turtles.

Posted in Infertility tagged , , at 1:40 pm by lifebytheday

We had our second consultation with the RE last night, and everything was largely as I expected.

  • Hormone levels – normal, with the exception of elevated testosterone (typical for PCOS)
  • S’s counts – normal
  • Clotting tests – normal (no reason why I experienced bleeding after last ER)
  • MRI – normal (no brain tumor, phew)
  • Genetic tests – normal

So what’s next?  Here’s what we discussed:

  • He’d like me to start back with Metformin (extended release, 2 tabs/1000 mgs, at night), although my insulin levels look normal, to make sure that nothing having to do with my sugars is affecting my ability to ovulate
  • I need to do 4-8 weeks of BCPs (probably around 6 weeks), to regain a more normal hormone balance and suppress my inflated LH levels.  I’ll be starting these as soon as they receive insurance approval for this cycle.
  • We will be using Lupron again (luteal Lupron) as part of my protocol.  I pushed him on this, and he said that this is absolutely needed in my case, to suppress my ovaries and prevent OHSS.
  • We will not be using Follistim as the second part of the protocol, but instead will be using a combination of two drugs, likely Gonal-F and Repronex.  He’s going to make the decision on that once he’s had a chance to more closely study how I responded to the Follistim (why he didn’t do that before this appt, I don’t know).
  • We will definitely be doing ISCI this time (because of the low fertilization rates previously), and potentially assisted hatching as well.
  • We will make a game time decision as to whether we’ll be transferring on day two, three, or five.  If the embryo quality and fertilization is better this time (which hopefully it will be!), we should have more embryos to choose from, in which case we’ll probably push out to day five.  The way he explained it to me is that if there are five or six very good embryos, they have no way of knowing on day three which one(s) will be the best, so they let them continue to grow and self-select.  If there are only one or two, then they’d transfer them earlier because the womb is a better incubator than the petri dish.  The one concern I had (that if we waited to day 5 that we couldn’t freeze the extra) is unfounded – they freeze all embies on day 5.
  • He is open to the idea of transferring two embryos, depending on the quality of the embies.  Again, if we have several perfect embies to choose from, we may put in one and freeze the rest.  But if there are two or more B-quality embies, I’m going to push for transferring two.
  • The antagonist protocol is not appropriate for me, and he seemed kind of annoyed when I asked him about it.  In fact, whenever I brought up something that I had researched or heard about, he seemed annoyed.  Like he didn’t want me doing my own armchair diagnosis – which I respect – but at least give me credit for doing my research and EXPLAIN to me why those things will or will not work!!  His personality still kind of rubs me the wrong way – despite being very nice, there’s just something about him that bugs me – but S likes him, and he’s a very good judge of character.  Plus, he’s just here to get me pregnant, not to take me out to dinner, right??  😉

So, right now we’re looking at a transfer probably mid- to end of January.  Pro – gives me a chance to get back on track with my diet and exercise and really enjoy the holidays.  Con – more WAITING, ugh!!  The only thing that’s left to do is a DNA/fragmentation test of S’s boys, since we’ll be bypassing nature’s self-selection with the ISCI.  This test isn’t covered by insurance, but our RE thinks it’s important to double check.  Apparently a capsule of liquid nitrogen arrives on our doorstep, with instructions for collection and shipping back.  The whole process sounds hysterical and I’ve already warned S that I’d be taking pictures…of the apparatus, not the “event,” don’t worry!   😉